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Interplay between HMOX1 and microorganisms in the gastrointestinal tract An important cause of intestinal inflammation is the infection by pathogenic bacteria, such as Salmonella enterica

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Moreover, the same group 261 further harnessed amber stop codon suppression in conjunction with specially engineered pyrrolysyl-tRNA synthetase variants to substitute the proximal histidine of Mb with ncAAs NMH, 5-thiazoylalanine (5ThzA), 4-thiazoylalanine (4ThzA), or 3-(3-thienyl)alanine (3ThiA)