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These synthetic statins are effective against a broader range of species and are effective at lower concentrations than fungal-derived statins (Natesan et al., 2008

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The flotation assay consisted of the incubation of PM-LUVs and LM-LUVs with α-SNAP WT or M105I and the subsequent flotation (after centrifugation) of the LUVs on a sucrose gradient to separate vesicle-bound proteins from unbound proteins (Fig