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Pathological changes in males and females fed 0.69 or 4.1 mg/kg bw per day included centrilobular hepatocellular hypertrophy, diffuse hyperplasia of the pituitary gland, feminization of the male mammary gland, mammary gland hyperplasia in females, cystic ovarian follicles, hypertrophy of the endometrium and endometrial glands in the uterus, degeneration of the seminiferous epithelium, and atrophy of the testes and acessory sex glands (Biegel et al., 1998b)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 54.Herman AC, Carlisle EM, Paxton JB, Gordon PV