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Moreover, the MTHFR gene polymorphisms have also been linked to cardiovascular diseases, stroke, psychiatric disorders, and certain types of cancer (24, 25, 26, 27, 28)

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This small case study is comprised of two test subjects, a 34 year-old male and a 47 year-old male, both of which have been on testosterone replacement therapy for greater than a five year duration, and both of which were verified and documented to have suppressed endogenous luteinizing hormone levels (0.1) prior to commencement of the study