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As a principal transcriptional regulator of intestinal iron transporters, HIF-2α plays a crucial role in maintaining systemic iron balance after birth ( in vitro ( Beyond iron transport, HIF signaling also shapes IBD through cell-type–specific immune programs, which helps reconcile seemingly conflicting findings across models

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The spectra quality requirement was full width half height linewidth less than 2.5 x standard deviation (SD) above the group mean