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Generation of transgenic lines To generate wild-type and mutant versions of PIF4pro::PIF4-mGFPmut2 transgenic lines, the pif4-2 and pifq mutant plants were transformed with wild-type or mutant versions of pJHA212H/PIF4pro::PIF4-(PT) 4 P-mGFPmut2- 6 His plasmids using the Agrobacterium -mediated floral dip method

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Patients using TB-500 at therapeutic doses of 2-2.5 mg twice weekly often report more stable blood pressure readings and improved exercise tolerance