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2 mg = 0.10 ml ( 10 units ) 50 mg vial + 2 ml water → 25 mg/ml - 1 mg = 0.04 ml ( 4 units )

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In a series of studies, de Groot and colleagues (de Groot et al., Reference de Groot, Smeets, Kaldewaij, Duijndam and Semin2012, Reference de Groot, Semin and Smeets2014, Reference de Groot, van Houtum, Gortemaker, Ye, Chen, Zhou and Smeets2018, Reference de Groot, Kirk and Gottfried2020, Reference de Groot, Kirk and Gottfried2021