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Tiotropium inhibits methacholine-induced extracellular matrix production via β-catenin signaling in human airway smooth muscle cells

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The antigenic, pyridoxal linkage site of GAD65 in GABA-producing gut microbes aligns closely with human GAD65 such that microbial GAD could conceivably sensitize enteric T-cells to GAD65 leading to the pathogenic immune destruction of β-cells