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Glutathione S-transferases (GSTs) regulate 4HNE concentrations GSTs belong to a family of multifunctional enzymes whose roles in detoxification of electrophilic xenobiotics or electrophilic metabolites is well established (Jakoby, 1978

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Initially, ORs are thought to be exclusive to the olfactory system, but emerging evidence indicates that ORs are also expressed in various extra-nasal tissues, including lungs ( Table 1 ), where they may be involved in diverse physiological and pathological processes