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Under hepatitis B virus (HBV) infection in vitro and in vivo, sulforaphane promotes macrophages to the pro-inflammatory M1 phenotype [374], while, under inflammatory conditions both in vitro and in vivo, it induces macrophages to change to the anti-inflammatory M2 phenotype [375], as explained in the various sections of this article

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The ability to normalize glucose metabolism before type 2 diabetes develops may alter health trajectories in ways that extend far beyond weight loss