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Integrating these complementary layers of information would allow for accurate stratification of patients with hyperactive NRF2 signaling, guiding the rational use of NRF2 inhibitors and combination regimens in HCC

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From the point of view of effective doses of selegiline, its antidepressant efficacy would be greater in CD157 KO mice than in WT mice or in the normal male ddY mice used by Shimazu et al