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The pharmacokinetics of bupropion, which is extensively metabolized by the CYP450 (CYP2B6), was not affected by moderate (~ 0.3–0.4 g/L) nor by high (~0.8 g/L) BACs (276)

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It keeps benzyl alcohol degradation rates low, maintains a consistent thermal environment regardless of seasonal or facility changes, and adds a meaningful buffer against the storage conditions that quietly shorten shelf life before a vial is ever opened