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The most studied angiogenic pathway stems from a 2017 study by Hsieh and colleagues, which combined a rat hind-limb model with cultured human vascular endothelial cells

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As development progresses, other cell types differentiate and establish connections within the retina in the following order: horizontal cells, cone photoreceptors, amacrine cells, rod photoreceptors, BPCs, and finally, Müller glial cells [94,95]