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It is FDA-approved for relapsing forms of MS and is the only peptide-class molecule with robust Phase III human trial evidence in MS

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Notably, levels of phosphorylated PDGFR-β and LRP1 (immunofluorescence, Supplemental Figure 13, A and B), as well as AKT and p42/p44 MAPK (Western blotting, Figure 11A) were comparable between Tβ4 +/Y and Tβ4 –/Y aortas after Imatinib treatment