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Recent reviews have synthesized CAA hallmarks across cancers (breast, colorectal, ovarian): proinflammatory outputs (IL-6/IL-8/CCL2/LIF/OSM), ECM remodeling, altered aromatase, and immune crosstalk that supports invasion, immune evasion, and therapy response

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Other therapeutic strategies under investigation involve targeting host cell pathways that either facilitate or inhibit viral replication, such as fatty acid synthesis and cholesterol trafficking pathways