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the differential response of the glutathione and NADP redox states to oxidative challenge in Δ glr1 and wild-type yeast and during reoxygenation in plants, the behaviour of NERNST closely mirrored that of the well-established E GSH sensor, roGFP2-Grx1, and particularly that of a free roGFP2, which can equilibrate with the glutathione redox couple via the action of endogenous glutaredoxins, and was opposite to that of the NAPstars

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These have been shown to have antioxidant, anti-inflammatory, cholesterol-lowering, immunomodulatory, and cardioprotective effects (Liberal et al., 2016)