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Methods: The current study used wild-type (WT) and intestine-specific Fgf15 knockout ( Fgf15 ile-/- ) mice fed a high-fat diet (HFD) for 3 months to induce obesity, at which point mice underwent sham surgery or SGx and were continued on HFD for 1- 3 months

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Studies show that the metabolic shift from aerobic glycolysis to oxidative phosphorylation serves as a crucial marker of neuronal differentiation (Zheng et al., 2016)