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A systematic review confirmed that NAC improves ovulation rate and hormonal parameters in PCOS (Thakker et al., Obstet Gynecol Int, 2015) [59]

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Importantly, of the phospho-sites identified by MS, pT292 lies within the GAP-F5 fragment (residues 252–359) of ArfGAP1 that is robustly phosphorylated by LRRK2 (Figure 1G)