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These fragments of LA formed by intestinal brush-border enzymes were synthesized and applied to the mucosal tissue during recovery during separate experiments, and one fragment, LA fragment 2 (VLVQPG) which has two glycine residues removed from NH 2 -terminus of LA, exhibited an inhibitory effect on recovery when given as 10 times overdose (10 μM) with 1 μM LA compared with untreated ischemia-injured tissue (49)