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AOD Peptide

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lower doses (1–2 mg) are preferred to avoid prolonged warfarin resistance INR 5.0–8.0 without bleeding : Withhold warfarin and consider 1–2 mg oral vitamin K if bleeding risk is high For neonatal prophylaxis , the standard UK regimen per NICE NG194 is 1 mg intramuscularly at birth for term infants, or alternatively, three oral doses (2 mg at birth, 1 week, and 4–6 weeks) for parents declining injection