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But when a significant amount of tendon is ruptured, it is best repaired surgically—as no amount of bleeding and scarring alone can reproduce the normal anatomy of a major ruptured tendon connected to a massive muscle

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In clinical trials, severe hypoglycemia, acute pancreatitis, gallstones, and cholecystitis occurred rarely and were observed only in a few cases during the use of high-dose semaglutide and tirzepatide [89,90]