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Results HFD feeding induces overt hyperglycemia and prevents body weight gain in Insr P1195L/ + mice P1195L/ + The blood glucose levels of Insr P1195L/ + mice under normal diet (ND) ( Insr P1195L/ +/ND mice) were not different from those of wild-type (WT) mice

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A vitamin B12 deficiency can develop slowly and symptoms may include: Persistent tiredness or low energy Shortness of breath Pale skin Pins and needles Memory or concentration difficulties If left untreated, deficiency can lead to more serious neurological complications