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Activation, differential localization, and regulation of the stress-activated protein kinases, extracellular signal–regulated kinase, c-Jun N-terminal kinase, and p38 mitogen-activated protein kinase, in synovial tissue and cells in rheumatoid arthritis

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TNF-alpha induces apoptosis mediated by AEBSF-sensitive serine protease (s) that may involve upstream caspase-3/CPP32 protease activation in a human gastric cancer cell line