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Binding of CCL2 to its receptor C-C chemokine receptor-2 (CCR2) in macrophages leads to the production of proinflammatory cytokines and chemokines such as TNFα, IL-1β, IL-12, and CXCL10 to exacerbate the inflammatory environment of the islet (125)

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Sperm characteristics in hypothyroid male albino rats treated with Vitex agnus castus Extract