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Common operations include: Total colectomy with ileostomy — the colon is removed and the end of the small intestine is brought out through the abdominal wall as a stoma, with stool collected in a bag Proctocolectomy with ileal pouch-anal anastomosis (J-pouch) — the colon and rectum are removed, and a pouch is created from the end of the small intestine and joined to the anus, restoring more normal bowel function over time Subtotal colectomy — in urgent situations such as severe flare unresponsive to medical treatment Even after the colon is removed, regular follow-up is important

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1 , 17 In cancer cells, 18 an augmented expression of PGC‐1α, 19 NRF1 and TFAM was reported, although these cells have a reduced number of mitochondria