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Although ARE/EpRE, AP-1 and NFκB may be responsible for basal expression and induction of GCLC by many of the pro- and anti-oxidants, recently c-Myc has been identified to also contribute to the basal expression and induction of human GCL under oxidative stress (Benassi et al., 2006)

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For people with particular health concerns, such as liver disease, high-risk factors, or complex medication regimens, it’s wise to consult a healthcare provider before starting glutathione