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MGST2 (microsomal glutathione S-transferase 2) is an important inflammatory mediator with leukotriene C4 synthase activity, involved in the biotransformation of arachidonic acid metabolites

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Deleting IGF-IR at the stage of osteoprogenitor development by Cre-lox recombination using an osterix promoter-driven Cre mouse line, results in delayed osteoblast maturation, matrix synthesis and mineralization, without affecting the differentiation or function of osteoclasts (57)