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2) GPX4-independent ferroptosis suppression—FSP1–CoQ10 pathway: Myristoylated ferroptosis suppressor protein 1 (FSP1), also known as apoptosis-inducing factor mitochondrial 2 (AIFM2), resides on the plasma membrane and functions as a CoQ10 reductase

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The high-oxygen lung microenvironment imposes strong selective pressure for lipid remodeling programs that stabilize membranes and buffer oxidative stress, rendering SCD1-dependent MUFA synthesis a critical adaptive mechanism

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