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Microglial BV-2 cell line incubated with conditioned media from SH-SY5Y cells over-expressing wild-type or mutant alpha-synuclein release proinflammatory cytokines such as TNF-alpha and IL1-alpha [270, 271]

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For example, curcumin has been used in traditional medicine because of its efficacy against kidney damage [153,154,155,156]