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The relative enzyme activity of rHrGSTm1 was the highest when pH 8.0, increased steadily when pH was 6.0–8.0, and decreased gradually when was pH 8.0–9.0 (Fig

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In an experiment investigating PXR and BAs excretion, administration of atorvastatin lowered BAs levels in the intestine, but was of no use in PXR knockout mice (128)