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Role of Free Radicals in the Pathophysiology of OSA: A Narrative Review of a Double-Edged Sword - PMC

These systems include a) enzymatic defences such as catalase, superoxide dismutase and glutathione that inhibit the formation of toxic OH - by metabolizing superoxide, H 2 O 2 and lipid peroxides, and b) entrapping free radical defences such as histidine-peptides, the iron-binding proteins transferring and ferritin, dihydrolipoic acid, reduced CoQ 10 , melatonin, urate and plasma protein thiols [24, 191-193]

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Glia 32 1–14 10.1002/1098-1136(200010)32:1 3.0.CO;2-W [DOI] [PubMed] [Google Scholar] Ankarcrona M., Dypbukt J