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As in the combination regimens of chemotherapeutics plus Tα1 adopted for treatment of many cancer types (Garaci et al., 2015), in MS a combination of disease modifying therapies with synthetic Tα1 may help in addressing and correctly modulating the repopulation of B cell compartment towards a more regulatory and anti-inflammatory phenotype

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He carried me and my pack up those hills and dug our foxhole by himself