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In fact, increased levels of various lipid peroxidation products, such as 4-hydroxynonenal (HNE), malondialdehyde (MDA), and F(2)/F(4)-isoprostane, have been detected in the plasma, CSF, and brains of subjects with AD and MCI [31,32,33], which also suggests the possibility of using lipid peroxidation products as markers for AD identification

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Interestingly, the distributional pattern of GABA within the pancreatic tissue closely resembles that of insulin [7], suggesting the correlation with increased insulin-secreting β cells observed following GABA treatments