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Its removal altered the meta-analysis results ( P = 0.052, Hedges g: − 0.99, 95% CI − 1.98 to − 0.01

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For summaries of comments received on burden as it relates to the repository, we refer readers to the discussions in the Collection of Information Requirements section of this final rule, which highlights CMS' interest in and efforts to reduce any burden associated with voluntary submissions to the 340B repository