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Mesenchymal stem cells (MSCs) and MSC-derived exosomes in animal models of central nervous system diseases: targeting the NLRP3 inflammasome

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However, when nutritional deprivation exceeds a critical threshold, ATP synthesis impairment leads to insufficient release of DAMPs, inhibiting antigen cross-presentation by dendritic cells (DCs), and ultimately weakening the immune activation efficacy of ICD (Krysko et al., 2012) (214)

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