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10.1016/j.mam.2008.08.006 [DOI] [PMC free article] [PubMed] [Google Scholar] Fujimori S., Abe Y., Nishi M., Hamamoto A., Inoue Y., Ohnishi Y., Nishime C., Matsumoto H., Yamazaki H., Kijima H., et al

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Notably, PDH-mediated proline catabolism is associated with tumor survival and metastasis, while MYC’s regulation of both proline synthesis and degradation highlights the oncogenic control over this metabolic pathway (134, 135)