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We previously reported a decrease in GS activity and a downregulation of protein expression associated with the Glu-Gln cycle, including GLT-1, SNAT-1, SNAT-2, SNAT-3, and SNAT-5, in the mPFC of mice with CIS-induced depression [14, 17, 18]

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Although LNPs used in the Pfizer-BioNTech and Moderna vaccines have not been studied, cationic molecules and cationic nanoparticles are known to activate the intracellular complement system in a membrane-damage-related process similar to how cationic lipids enable mRNA escape from the lysosomes into the cytoplasm 75