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These data suggest that protective mechanisms observed with AMIN involve decreased LTC(4)/D(4)/E(4) mediated pulmonary capillary permeability and attenuated lipid peroxidation

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At the end of the SURMOUNT-4 study (88 weeks from baseline), 25.9% of people at the placebo group were able to achieve ≥ 15% WL compared to 84.1% at the tirzepatide group