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5-amino-1mq distribution 5-amino-1mq shows a different distribution profile: Moderate distribution to peripheral tissues Lower volume of distribution compared to SLU-PP-332 Limited penetration of the blood-brain barrier The distribution pattern of 5-amino-1mq may make it more suitable for certain therapeutic applications while limiting its use in others

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Although the serum glycerol levels were similarly increased in WT/HFD mice and Insr P1195L/ +/HFD mice, the blood glucose levels after CL316432 administration were significantly higher in Insr P1195L/ +/HFD mice, indicating that enhanced lipolysis exacerbates hyperglycemia in Insr P1195L/ +/HFD mice