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A pharmacogenomic study reported that neurotoxicity above grade 2 was correlated with single-nucleotide polymorphisms in ABCC1 [rs2074087: odds ratio = 0.43 (0.22-0.86)], and ABCC2 [rs3740066: 2.99 (1.16-7.70)

it follows that carnitine supplementation ensures an adequate supply of oxygen to the muscle