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29 and ultrasound-based therapies include sonodynamic therapy (SDT), 14 but also sonopermeation approaches, which combine microbubbles and ultrasound to enhance chemo-, nano-, and immunotherapies

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For instance, two quinolone antibiotics, norfloxacin and ciprofloxacin, are lipophilic bases accumulating in the lysosomal lumen and exert detergent-like effects on the lysosomal membrane