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There is meaningful interest in GHK-Cu for skin regeneration and remodeling, but patients should know the evidence is still not the same as having large, acne-scar-specific human trials proving strong visible improvement in post-Accutane scarring

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Funding This study was supported by grants from the National Natural Science Foundation of China (82272659, 82473299), the Natural Science Foundation of Hunan Province (2024JJ2092, 2024JJ5560, 2023JJ30323), and the Clinical Research Center for Pediatric Solid Tumors in Hunan Provincial (2023SK4058)