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A slightly opposing study, however, was reported no immunological benefit of selenium in patients with moderate disease activity (in terms of TPOAb and cytokine production patterns) may not (equally) benefit as patients with high disease activity (108.3)

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4 The ferroptosis-immune-metabolic axis in COPD The interplay between ferroptosis, immune dysregulation, and metabolic rewiring—collectively termed the “ferroptosis-immune-metabolic axis”—is a central driver of COPD pathogenesis