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10.5194/bg-15-2449-2018 Biogeosciences 65 JiaoG.YuG.ZhangJ.EwartH

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COX17 also aids in the oxidative respiratory chain by transferring Cu + to MT-CO1/COX1 and COX11 ( + to the Golgi, where it binds to ATP7A/B ( + excretion and regulating elevated Cu + levels through Golgi-lysosomal translocation ( + to the nucleus ( + , reducing ROS oxidative stress via a Fenton-like reaction (Zhang et al., 2022), and ATOX1 serves as a target for mitigating intracellular free Cu + damage

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