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The Role of FRα in Cancer FRα’s expression is minimal in normal cells, yet it is significantly overexpressed in a variety of solid tumors, including mesothelioma (72-100%), triple-negative breast cancer (35-68%), ovarian cancer (76-89%), and non-small cell lung cancer (14-74%)
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We propose that using a neutralizing antibody to inhibit IL-10 and limit its potential effects on the immune system in the early stages of COVID-19 may be valuable for testing