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But even tiny changes or differences in your eye structure — including those that happen because of inflammation — can be enough to cause uveitis symptoms

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Nrf2 knockout animal models showed an increase in NF-κB activity and upregulation of its downstream target genes (such as TNF-α, IL-1β and IL-6 production) confirming the negative interplay between Nrf2 and NF-κB (Gao et al., 2021)