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Inflammation associated with diabetes in mice has been effectively ameliorated by sulforaphane, as shown in high-fat diet- or STZ-induced diabetes and cardiomyopathy [200,201], db / db diabetic mice cardiomyopathy [202], diabetic cardiomyopathy in both type 1 and type 2 diabetes [203,204], high-fat diet-induced diabetes [205,206], ob/ob diabetic mice [90], obesity- and type 2 diabetes-associated pain [207], STZ-induced diabetes [208,209], STZ-induced diabetic nephropathy [210], type 1 diabetic OVE26 mice [211], and diabetes-induced vascular inflammation and pathogenesis [212]