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In response to this feedback from interested parties, in the CY 2025 PFS proposed rule (89 FR 61971 through 61972) we solicited comments on establishing a repository in a future year of the Medicare Part D Drug Inflation Rebate Program to comply with the requirement under section 1860D-14B(b)(1)(B) of the Act that CMS shall exclude from the total number of units for a Part D rebatable drug those units for which a manufacturer provided a discount under the 340B Program

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Your pharmacy beyond-use date is the definitive reference, not the brand-name 21-day window If you are currently using a compounded tirzepatide starting dose , verify your specific vial storage requirements with the dispensing pharmacy before travel