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Overview of MG The present section describes the pathogenesis of MG, immunomodulatory therapy for MG, the regulatory mechanism of IL-35 in MG and the regulatory mechanism of IL-35 in MG through the regulation of Bregs and Tregs, as follows: Pathogenesis of MG MG is an autoimmune disorder characterized by autoantibodies targeting AChRs or other associated proteins, such as muscle-specific kinase (MuSK) and low-density lipoprotein receptor related protein 4 (LRP4), on the postsynaptic membrane (77)

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