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182 This study also showed that curcumin-galactomannan (1000 mg/day) supplementation resulted in a remarkable increase in α- and β-waves of the brain and decreased the α/β ratio, audio-reaction time, choice-based visual reaction time, and improved memory in these volunteers

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This led to compounds like GHRP-6, GHRP-2, and eventually sermorelin—the first FDA-approved growth hormone releasing peptide (approved in 1997 as Geref)